Comparison of Radioimmuno and Carbon Nanotube Field-Effect Transistor Assays for Measuring Insulin-Like Growth Factor-1 in a Preclinical Model of Human Breast Cancer
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Comparison of Radioimmuno and Carbon Nanotube Field-Effect Transistor Assays for Measuring Insulin-Like Growth Factor-1 in a Preclinical Model of Human Breast Cancer
BACKGROUND To realize the promise of personalized medicine, diagnostic instruments used for detecting and measuring biomarkers must become smaller, faster and less expensive. Although most techniques used currently to detect biomarkers are sensitive and specific, many suffer from several disadvantages including their complexity, high cost and long turnaround time. One strategy to overcome these...
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In this article, a new structure is presented for MOS (Metal Oxide Semiconductor)-like junctionless carbon nanotube field effect transistor (MOS-like J-CNTFET), in which dual material gate with different work-functions are used. In the aforementioned structure, the size of the gates near the source and the drain are 14 and 6 nm, respectively, and the work-functions are equal and 0.5 eV less tha...
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Background and aims: Laron syndrome is a disease that treated by Insulin-like Growth Factor 1 (IGF-1). This protein is a single chain and has three disulfide bonds. People with Laron syndrome have low rates of cancer and diabetes, although they appear to be at increased risk of casual death due to their stature. IGF-1 is synthesized by many tissues and is secreted from liver as an endocrine hor...
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Title of Document: DEVELOPMENT OF CARBON NANOTUBE FIELD-EFFECT TRANSISTOR ARRAYS FOR DETECTION OF HER2 OVEREXPRESSION IN BREAST CANCER Konrad Hsu Aschenbach, Ph.D., 2011 Directed By: Professor Romel D. Gomez, Department of Electrical and Computer Engineering We developed a carbon nanotube biosensor platform that was deployed at the National Cancer Institute and successfully detected the HER2 on...
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ژورنال
عنوان ژورنال: Journal of Nanobiotechnology
سال: 2011
ISSN: 1477-3155
DOI: 10.1186/1477-3155-9-36